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Journal:
Article Title: Identification of biomarkers for ovarian cancer using strong anion-exchange ProteinChips: Potential use in diagnosis and prognosis
doi: 10.1073/pnas.2033602100
Figure Lengend Snippet: Differentially expressed ovarian cancer-associated serum proteins. (A) Detection of differentially expressed ovarian cancer-associated serum proteins. A representative pseudogel view of SELDI-TOF-MS analysis of serum samples, processed on a SAX2 chip surface, shows relative abundance of potential ovarian cancer markers. The six spectral protein profiles at the top represent serum from healthy individuals, three benign samples are represented in the middle section, and the six spectral profiles on the bottom represent serum from patients with ovarian cancer. (B) Representative spectral overlay of serum from a healthy (solid line) vs. diseased (dashed line) individual. The overlay shows that there is a decrease of protein 13.9kDa in serum from ovarian cancer patients, whereas concurrently there is an increase of the proteins 15.1kDa and 15.9kDa. Numbers in the mass spectra represent the observed mass of the marker in that particular sample.
Article Snippet:
Techniques: Marker